The most damning evidence the government can present a jury is a confession. The government knows this, and this is why federal agents and state law officers are trained in interrogative techniques. And that is why they do what they can to cajole an arrestee into talking about the charges before that arrestee ever sees or talks to an attorney.

Here is the best advice: Do not say anything until you have spoken with a lawyer.  

People think of law enforcement as their protectors, their guard against bedlam. That may be true, but once the government investigates a person it becomes that person's adversary. During an investigation or an arrest agents might say, "If you talk to us you can help yourself." (Who hasn't seen that on NCIS or Chicago Blue?) But that is invariably not true. The solicitation is to gain evidence against you before your attorney intervenes and tells you to remain silent. If you don't feel comfortable remaining silent (due to a recent Supreme Court case you probably don't have the option of remaining silent), tell the agents you want a lawyer.

Agent:  Would you like to help yourself? 
You:     I want to speak to a lawyer.
Agent:  If you talk to me now you can help yourself. 
You:    I want to speak to a lawyer.
Agent: I can't do anything for you once you get a lawyer.
You:    I want to speak to a lawyer.
Agent: How 'about them Cowboys?
You:    I want to speak to a lawyer.

Cooperation might be the best way to handle the case, but consult with your lawyer about that before you go down that road.  Remember always: Attorney first, talking second.